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Instaflex Muscle Support Review

Instaflex claims its product Muscle Support has been scientifically formulated to reduce cramping, treat soreness, and muscle recovery rate.

With only 6 ingredients – almost all vitamins and minerals – Muscle Support seems quaint compared to other supplements. However, it is retailed at most major supplement stores, which lets me think it must be somewhat effective.

Let’s research the ingredients and see what customers are reporting before we rule it one way or the other.


Instaflex Muscle Support is comprised of the following ingredients:

Vitamin D3 400 IU. Vitamin D3 reduces bone fractures, and greatly increases musculoskeletal strength. [1] Recommended vitamin D dosage is 400-1000 IU daily. [2]

Vitamin E 30 IU. Vitamin E treats conditions like heart attack, chest pain, leg pain due to hard or blocked arteries, high blood pressure, diabetes, and cancer. It may also be used to reduce muscle damage following exercise, improving strength, and increasing energy.

Vitamin E-deficient adults should aim for 60-75 IU, but anywhere from 100-2000 IU is recommended for various health concerns. [3] Instaflex Muscle Support contains low enough vitamin E to increase muscle performance.

Calcium 300 mg. One study shows muscle contractions, plasticity, and function depend on calcium. It may even be crucial for altering muscle growth and removing muscle disease. [4]

For most minor treatments, 1-3 g calcium is generally recommended. [5] This product contains 30% daily calcium requirements and is likely to increase muscle function.

Magnesium 150 mg. One study found magnesium was significantly associated with increased muscle performance. Older subjects given a magnesium serum performed better with grip strength, lower-leg muscle power, knee extension torque, and ankle extension strength. Researchers concluded magnesium concentration has independent correlation in muscle performance, and more research is needed to determine whether supplementation improves muscle function. [6]

Most experts recommend 1-4 g magnesium, which is more than Muscle Support has in its entire blend. Consequently, you’ll need to turn to outside sources to obtain recommended amounts. [7]

Potassium 99 mg. One animal study showed proper potassium levels prevent swelling of the cell that results in inhibited muscle contraction. Potassium was linked to higher production of smooth muscle cell membranes and better muscle contraction. [8]

Adults are advised to supplement potassium up to 4-5 g per day. Although Instaflex contains a fraction of that amount, it could still positively impact muscle health and performance. [9]

L-Glutamine Monohydrate 500 mg. One study found patients who received 1.2 g amino acids and .3 g l-alanyl-l-glutamine recovered from surgery significantly faster (6.2 days shorter on average) than the control group with 1.5 g amino acids. This evidence suggests glutamine plays an important role in muscle repair. [10]

Another study showed male and female athletes benefited from supplementing with creatine monohydrate and l-glutamine monohydrate (4 g). Their body composition, vertical jumps, and cycle performances, body mass, and initial rate of power production also increased. [11]

Instaflex Muscle Support contains approximately one gram more than the effective studied dose, so it should positively impact muscle growth and repair.


Instaflex recommends taking Muscle Support for 3 months to observe the full effects before deciding against it; however, it is likely you will start seeing and feeling effects after 7 days.

Serving size is 3 capsules, and there are 30 servings per bottle.

Health Concerns

Glucosamine is derived from shellfish, namely shrimp and crab. If customers have shellfish allergies, are taking other medication, or are pregnant or nursing, consult a physician before use.

Caution should always be exercised when supplementing with vitamins and minerals, but especially with fat-soluble vitamins like vitamin E. Fat-soluble vitamins, like vitamin E, store excess quantities in fat cells, and, though rare, can cause serious side effects, such as flu-like symptoms, blurred vision, rash, bruising, bleeding, hemorrhagic stroke, and even death. [3]

Price sells Muscle Support for $26.99.

Retailers like GNC, Walgreens,, and usually sell it for $24.99. has a promotion where a customer buying products totaling $25 can purchase Muscle Support for $3.99.

Return Policy

Instaflex offers a free 14-day trial and a 30-day money-back guarantee. Customers have 18 days after starting the free trial to cancel before the next shipment is mailed.

After the free trial – if customers decide against Instaflex and wish to receive a refund, the rest of the product must be mailed within 30 days of the date it was shipped.

Instaflex can be cancelled any other time, so future shipments and payments will cease.


Instaflex Muscle Support reviews seem mostly positive. They can be found on several different reputable sites, aiding to the customers’ credibility. Also, has a “verified customer” feature that shows readers the comments they read are from actual customers who purchased the product.

Negative comments are much fewer, but are still important to consider.

“I have been using this product for over a month now and have noticed a big difference. A year or so ago I severely sprained my knee (wrecked a motorcycle, when I hit the ground my leg bent sideways). Wore a knee immobilizer for 3 weeks and Dr. said I was good to go. Ever since then my knee has been hurting so bad, best way to describe it would be a sore burning sensation. After using this product (just 1 pill a day instead of the recommended 3) I no longer have that pain. I would recommend this product to anyone with pain associated to sprains.” – Derek Sheck

“Probably a good product, but it didn’t seem to make a difference in my pain. I need something more – not sure what.” – Rachel C. Trotter

“I am a distance runner and last year I struggled with severe muscle cramps on long runs in my right calf. Talked to some GNC folks and they recommended I try this product when it came out. Tried it and love it. I’ve been taking it for 2 months now, in January I ran over 140 miles with long runs of 10,13,13,15 miles with no calf issues. I truly feel Instaflex Muscle Support has made a difference. Hope this helps.” – Eric.campbell1


Instaflex Muscle Support contains vitamins, minerals, and an amino acid – all ingredients tested and suggested by reputable research to influence muscle recovery and performance. There are no gimmick-ingredients with sketchy “evidence” that seems questionable.

It is interesting to note not all customers claimed it made a difference for them. However, most reviewers had positive comments, and many talked about how it impacted their rigid athletic routines.

I would recommend this product as a solid buy based on positive comments, the research behind the ingredients, fair price, and the limited side effects.


[1] Pérez-López FR. “Vitamin D and its implications for musculoskeletal health in women: An update.” Maturitas. 2007 Jun 28. Available from:

[2] “Vitamin D.” WebMD. Available from:

[3] “Vitamin E.” WebMD. Available from:

[4] Berchtold, MW; Brinkmeier, H; Huntener, M. “Calcium ion in skeletal muscle: its crucial role for muscle function, plasticity, and disease.” Physiology Reviews. 2000. Available from:

[5] “Calcium.” WebMD. Available from:

[6] Dominquez, LJ, M Barbagallo, et al. “Magnesium and muscle performance in older persons: the InCHIANTI study.” American Journal of Clinical Nutrition. 84.2 (2006): 419-26. Available from:

[7] “Magnesium.” WebMD. Available from:

[8] Karaki, H.; Urakawa, N.; Kutsky, P. “Potassium-induced contraction in smooth muscle.” Nihon Heikatsukin Gakkai Zasshi. 1984. Available from:

[9] “Potassium.” University of Maryland Medical Center. 2011. Available from:

[10] Morlion, BJ; Stehle, P; Wachtler, P; et al. “Total parenteral nutrition with glutamine dipeptide after major abdominal surgery: a randomized, double-blind, controlled study.” Annals of Surgery. 1998. Available from:

[11] Lehmkuhl, M., Malone, M., Justice, B., et al. “The effects of 8 weeks of creatine monohydrate and glutamine supplementation on body composition and performance measures.” Journal of Strength Conditioning Research. National Strength and Conditioning Association. 2003. Available from:

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